"The relationship between cardiometabolic risk factors and enterolignans (enterolactone and enterodiol)"

Year: 2015

Institution: Albert Einstein College of Medicine / New York University School of Medicine

Principal Investigator: Dr. Jeanette Beasley

Research Category: Basic Science


Polyphenols are plant metabolites rich in fruit, vegetables, legumes, cereals, cocoa/chocolate, coffee, tea, and wine. Due to their high antioxidant potential, they have more recently been considered as agents for preventing and treating oxidative stress-related diseases, including cardiovascular disease.

This project examines eight selected polyphenols (enterolactone, enterodiol, resveratrol, daidzein, equol, naringenin, hesperetin, and quercetin) having preliminary evidence of associations with obesity and other cardio-metabolic risk factors in prior studies. It also provides the long-term potential to examine how selected polyphenols relate to other health conditions, such as diabetes and cancer in order to better understand the mechanisms by which polyphenols influence chronic disease risk.


The above project description has been supplied by the Principal Investigator